| Gene Symbol | VAMP4 |
|---|---|
| Entrez Gene | 8674 |
| Alt Symbol | VAMP-4, VAMP24 |
| Species | Human |
| Gene Type | protein-coding |
| Description | vesicle-associated membrane protein 4 |
| Other Description | - |
| Swissprots | Q96J20 Q9UEL7 O75379 Q96IY9 A2IDD8 |
| Accessions | EAW90904 EAW90905 EAW90906 EAW90907 EAW90908 EAW90909 O75379 AF044310 AAC24032 AF052100 AK056124 AK123624 AK290441 BAF83130 AL035296 CAA22896 BC005974 AAH05974 BC007019 AAH07019 BC031264 AAH31264 CR457011 CAG33292 DB167275 XR_426805 NM_001185127 NP_001172056 NM_003762 NP_003753 NR_033704 NM_201994 |
| Function | Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. |
| Subcellular Location | Golgi apparatus, trans-Golgi network membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles. |
| Top Pathways | SNARE interactions in vesicular transport |