| Gene Symbol | CTF1 |
|---|---|
| Entrez Gene | 1489 |
| Alt Symbol | CT-1, CT1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | cardiotrophin 1 |
| Other Description | cardiophin 1|cardiotrophin-1 |
| Swissprots | A8MVX4 Q16619 Q5U5Y7 |
| Accessions | AAD12173 EAW52192 Q16619 BC036787 AAH36787 BC049822 BC064416 AAH64416 U43030 AAA85229 XM_011545759 XP_011544061 XM_011545760 XP_011544062 NM_001142544 NP_001136016 NM_001330 NP_001321 |
| Function | Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes. |
| Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |