ATP6V1C1

Gene Symbol ATP6V1C1
Entrez Gene 528
Alt Symbol ATP6C, ATP6D, VATC, Vma5
Species Human
Gene Type protein-coding
Description ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
Other Description H(+)-transporting two-sector ATPase, subunit C|H+ -ATPase C subunit|H+-transporting ATPase chain C, vacuolar|V-ATPase C subunit|V-ATPase subunit C 1|V-type proton ATPase subunit C 1|subunit C of vacuolar proton-ATPase V1 domain|vacuolar ATP synthase subunit C|vacuolar proton pump C subunit|vacuolar proton pump subunit C 1|vacuolar proton pump, 42-kD subunit|vacuolar proton-ATPase, subunit C, VI domain
Swissprots P21283
Accessions AAL50383 CAD33297 EAW91859 EAW91860 P21283 AA242944 AK000064 AK090702 AK298617 BAH12829 AK308632 AL707882 AU137773 AV649881 AW505309 BC010960 AAH10960 BI821321 BX648079 EU832346 ACE87603 EU832431 ACE86916 HQ447211 ADQ31698 J05682 AAA36803 X69151 CAA48903 NM_001695 NP_001686 NM_001007254
Function Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:12384298}.
Top Pathways Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis