CCNT2

Gene Symbol CCNT2
Entrez Gene 905
Alt Symbol CYCT2
Species Human
Gene Type protein-coding
Description cyclin T2
Other Description SDS-stable vimentin-bound DNA fragment HEF42VIM22|cyclin T2a|cyclin T2b|cyclin-T2|subunit of positive elongation transcription factor b
Swissprots O60582 Q5I1Y0 D3DP74 O60583 Q53SR4 Q29R66 D3DP73 A8KA48
Accessions AAW56073 AAY14998 EAX11644 EAX11645 EAX11646 EAX11647 O60583 AF048731 AAC39665 AF048732 AAC39666 AK023645 AK075041 AK292913 BAF85602 AK294889 BAG57982 AU157699 BC114366 AAI14367 BX648174 XM_006712827 XP_006712890 XM_011512132 XP_011510434 XM_011512133 XP_011510435 XM_011512134 XP_011510436 NM_001241 NP_001232 NM_058241 NP_490595 NR_037649
Function Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). {ECO:0000269|PubMed:10364329}.
Subcellular Location Nucleus.
Tissue Specificity Ubiquitously expressed.
Top Pathways Transcriptional misregulation in cancer