| Gene Symbol | SI |
|---|---|
| Entrez Gene | 6476 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | sucrase-isomaltase (alpha-glucosidase) |
| Other Description | oligosaccharide alpha-1,6-glucosidase|sucrase-isomaltase, intestinal |
| Swissprots | Q1RMC2 P14410 A2RUC3 Q1JQ80 |
| Accessions | EAW78601 P14410 AA376756 BC115033 BC115034 AAI15035 BC116452 AAI16453 BC116453 BC132834 AAI32835 BC132860 AAI32861 BG187733 DA919374 M22616 AAA60551 X63597 CAA45140 XM_011513078 XP_011511380 NM_001041 NP_001032 |
| Function | Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides. {ECO:0000269|PubMed:20356844}. |
| Subcellular Location | Apical cell membrane; Single-pass type II membrane protein. Note=Brush border. |
| Tissue Specificity | Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon. {ECO:0000269|PubMed:1677636}. |
| Top Pathways | Carbohydrate digestion and absorption, Galactose metabolism, Starch and sucrose metabolism |