ATP5G1

Gene Symbol ATP5G1
Entrez Gene 516
Alt Symbol ATP5A, ATP5G
Species Human
Gene Type protein-coding
Description ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
Other Description ATP synthase F(0) complex subunit C1, mitochondrial|ATP synthase lipid-binding protein, mitochondrial|ATP synthase proteolipid P1|ATP synthase proton-transporting mitochondrial F(0) complex subunit C1|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)|ATPase protein 9|ATPase subunit 9|ATPase subunit C|mitochondrial ATP synthase, subunit 9|mitochondrial ATP synthase, subunit C
Swissprots P05496
Accessions CAA49532 EAW94705 EAW94706 P05496 AK095669 AK311848 BAG34790 AL080089 CAB45704 AM393437 CAL38315 BC004963 AAH04963 BF573360 BG611396 BT007230 AAP35894 BU596803 CF129854 CR533449 CAG38480 D13118 BAA02420 M16453 AAA51806 NM_001002027 NP_001002027 NM_005175 NP_005166
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
Subcellular Location Mitochondrion membrane; Multi-pass membrane protein.
Top Pathways Alzheimer's disease, Huntington's disease, Oxidative phosphorylation