| Gene Symbol | NME3 |
|---|---|
| Entrez Gene | 4832 |
| Alt Symbol | DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | NME/NM23 nucleoside diphosphate kinase 3 |
| Other Description | NDK 3|NDP kinase 3|NDP kinase C|non-metastatic cells 3, protein expressed in|nucleoside diphosphate kinase 3|nucleoside diphosphate kinase C |
| Swissprots | Q9BWH4 Q13232 |
| Accessions | AAK61291 CAB72319 EAW85629 Q13232 AK308663 BC000250 AAH00250 BG911570 DQ892515 ABM83441 EU176697 ABW03498 U29656 AAA85097 XM_005255332 XP_005255389 XM_011522503 XP_011520805 XM_011522504 XP_011520806 NM_002513 NP_002504 |
| Function | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis. |
| Top Pathways | Purine metabolism, Pyrimidine metabolism |