GPX3

Gene Symbol GPX3
Entrez Gene 2878
Alt Symbol GPx-P, GSHPx-3, GSHPx-P
Species Human
Gene Type protein-coding
Description glutathione peroxidase 3
Other Description GPx-3|extracellular glutathione peroxidase|glutathione peroxidase 3 (plasma)|plasma glutathione peroxidase
Swissprots Q86W78 Q9NZ74 Q9UEL1 O43787 P22352
Accessions AAP50261 BAA03862 BAA03863 BAA03864 EAW61692 EAW61693 P22352 AF217787 AAF43005 AK310242 AL036834 BC013218 BC013601 AAH13601 BC025956 BC035841 AAH35841 BC050378 AAH50378 BC066949 AAH66949 BI522602 D00632 BAA00525 X58295 CAA41228 NM_002084 NP_002075
Function Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
Subcellular Location Secreted.
Tissue Specificity Secreted in plasma.
Top Pathways Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism