TUSC3

Gene Symbol TUSC3
Entrez Gene 7991
Alt Symbol D8S1992, M33, MRT22, MRT7, N33, OST3A
Species Human
Gene Type protein-coding
Description tumor suppressor candidate 3
Other Description Putative prostate cancer tumor suppressor|magnesium uptake/transporter TUSC3|oligosaccharyltransferase 3 homolog A
Swissprots D3DSP2 Q14912 A8MSM0 Q13454 Q96FW0 Q14911
Accessions AAB18375 AAB18376 EAW63837 EAW63838 EAW63839 Q13454 AF028729 AI366810 AK026149 AY530159 AAS18677 AY562998 AAS75588 AY562999 AAS75589 BC010370 AAH10370 BT020002 AAV38805 BX641112 DA796279 DQ892936 ABM83862 DQ896185 ABM87184 U42349 AAB18374 XM_011544651 XP_011542953 XM_011544652 XP_011542954 XM_011544653 XP_011542955 XM_011544654 XP_011542956 NM_006765 NP_006756 NM_178234 NP_839952
Function Magnesium transporter (PubMed:19717468). May be involved in N-glycosylation through its association with N-oligosaccharyl transferase (PubMed:24685145). {ECO:0000269|PubMed:19717468, ECO:0000303|PubMed:12887896, ECO:0000303|PubMed:24685145}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas. {ECO:0000269|PubMed:12887896}.
Top Pathways N-Glycan biosynthesis, Protein processing in endoplasmic reticulum