| Gene Symbol | MTHFR |
|---|---|
| Entrez Gene | 4524 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | methylenetetrahydrofolate reductase (NAD(P)H) |
| Other Description | 5,10-methylenetetrahydrofolate reductase (NADPH)|methylenetetrahydrofolate reductase |
| Swissprots | Q7Z6M6 Q9UQR2 B2R7A6 P42898 Q5SNW9 Q8IU73 Q5SNW6 |
| Accessions | AAD17965 AAG33979 AAN40863 AAN40864 AAN40865 AAP88033 AAZ03741 ABB17330 ABK34493 CAB81551 CAB81552 EAW71708 EAW71709 P42898 AB209113 BAD92350 AJ237672 CAB41971 AK312907 BAG35753 AY046560 AAL17646 AY046561 AAL17647 AY046562 AAL17648 AY046563 AAL17649 AY046564 AAL17650 AY046565 AAL17651 BC011614 BC018766 BC053509 AAH53509 CN355286 JQ429447 AFQ62002 U09806 AAA74440 XM_005263458 XP_005263515 XM_005263460 XP_005263517 XM_005263461 XP_005263518 XM_005263462 XP_005263519 XM_005263463 XP_005263520 XM_011541495 XP_011539797 XM_011541496 XP_011539798 NM_005957 NP_005948 |
| Function | Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine. |
| Top Pathways | Carbon metabolism, One carbon pool by folate |