| Gene Symbol | Cyp24a1 |
|---|---|
| Entrez Gene | 13081 |
| Alt Symbol | 24-OHase, CP24, Cyp24 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | cytochrome P450, family 24, subfamily a, polypeptide 1 |
| Other Description | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial|25-hydroxyvitamin D-24-hydroxylase|cytochrome P450 24A1|cytochrome P450, 24|cytochrome P450, 24a1|cytochrome P450-CC24|vitamin D(3) 24-hydroxylase |
| Swissprots | Q64441 |
| Accessions | EDL06583 Q64441 AK016668 AK143984 BAE25646 AK159109 BAE34825 AK159481 BAE35118 AK159527 BAE35156 AK159852 BAE35429 AK159954 BAE35510 AK159976 BAE35528 AK164697 BAE37882 BC109139 AAI09140 BC109140 AAI09141 D49438 BAA08416 D89669 BAA21843 NM_009996 NP_034126 |
| Function | Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. |
| Subcellular Location | Mitochondrion. |
| Top Pathways | MicroRNAs in cancer, Steroid biosynthesis |