MSI1

Gene Symbol MSI1
Entrez Gene 4440
Alt Symbol -
Species Human
Gene Type protein-coding
Description musashi RNA-binding protein 1
Other Description RNA-binding protein Musashi homolog 1|musashi-1|musashi1
Swissprots Q96PU1 Q96PU2 Q96PU0 O43347 Q96PU3
Accessions AAB95636 CBF67590 CBU92464 EAW98185 EAW98186 EAW98187 O43347 AB012851 BAA33962 AB072590 BAB69767 AB072591 BAB69768 AB072592 BAB69769 AB073212 BAB70469 AI583233 AK023262 BAG51178 BC140380 AAI40381 BC146463 AAI46464 BX393884 XM_006719403 XP_006719466 XM_006719404 XP_006719467 XM_011538361 XP_011536663 XM_011538362 XP_011536664 XM_011538363 XP_011536665 XM_011538364 XP_011536666 XM_011538365 XP_011536667 XM_011538366 XP_011536668 XM_011538367 XP_011536669 XM_011538368 XP_011536670 XM_011538369 XP_011536671 XM_011538370 XP_011536672 XM_011538371 XP_011536673 NM_002442 NP_002433
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. {ECO:0000269|PubMed:12054577, ECO:0000269|PubMed:9790759}.
Top Pathways mRNA surveillance pathway