| Gene Symbol | PLA2G7 |
|---|---|
| Entrez Gene | 7941 |
| Alt Symbol | LDL-PLA2, LP-PLA2, PAFAD, PAFAH |
| Species | Human |
| Gene Type | protein-coding |
| Description | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| Other Description | 1-alkyl-2-acetylglycerophosphocholine esterase|2-acetyl-1-alkylglycerophosphocholine esterase|LDL-PLA(2)|LDL-associated phospholipase A2|PAF 2-acylhydrolase|PAF acetylhydrolase|gVIIA-PLA2|group-VIIA phospholipase A2|lipoprotein-associated phospholipase A2|platelet-activating factor acetylhydrolase |
| Swissprots | Q15692 Q5VTT1 A5HTT5 Q13093 Q8IVA2 |
| Accessions | ABQ01234 EAX04301 EAX04302 Q13093 AK290381 BAF83070 AK294471 BAG57699 AK297066 BAG59587 BC025674 BC038452 AAH38452 BP326231 HQ448549 ADQ33028 U20157 AAC50126 U24577 AAB04170 XM_005249408 XP_005249465 XM_005249409 XP_005249466 NM_001168357 NP_001161829 NM_005084 NP_005075 |
| Function | Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids. |
| Subcellular Location | Secreted, extracellular space. |
| Tissue Specificity | Plasma. |
| Top Pathways | Ether lipid metabolism |