| Gene Symbol | HLA-G |
|---|---|
| Entrez Gene | 3135 |
| Alt Symbol | MHC-G |
| Species | Human |
| Gene Type | protein-coding |
| Description | major histocompatibility complex, class I, G |
| Other Description | HLA G antigen|HLA class I histocompatibility antigen, alpha chain G|HLA class I molecule|HLA-G histocompatibility antigen, class I, G|MHC class I antigen G|b2 microglobulin |
| Swissprots | P17693 |
| Accessions | AAA17890 AAA98745 AAB59351 AAC24826 AAC50997 AAC51855 AAC51856 AAC51857 AAC51858 AAC51859 AAC51863 AAF25961 AAK38203 AAL40074 AAM74993 AAM74994 AAM74995 AAM74996 AAM74997 AAM74998 AAM74999 AAM75000 AAM75001 AAM75002 AAM75003 AAM75004 AAM75005 AAQ13400 AAT73243 AAT73244 AAT73245 AAT73246 AAT73247 AAT73248 AAT73249 AAT73250 AAT73251 AAT73252 AAT73253 AAT73254 AAT73255 AAT73256 AAT73257 AAT73258 AAT73259 AAT74562 AAT74563 AAT74564 AAT74565 AAT74566 AAT76793 AAT76794 AAT76795 AAT76796 AAT76797 AAT76798 AAT76964 AAT76965 AAT76966 AAT76967 AAT76968 AAT76969 AAT76970 AAT81378 AAT81379 AAT81380 AAT81381 AAT81382 AAT81383 AAT81384 AAT81385 ABQ12153 ABQ12154 ABQ12155 ABQ12769 ABQ51012 ABY21168 ACA50440 ACA50441 ACH69971 ACH69972 ACH69973 ACH69974 ACH69975 ACN92040 ACN92041 ACN92042 ACN92043 ACN92044 ACN92045 ACO25292 ACZ37195 ACZ37196 ADB85517 ADL40397 ADN34672 ADN34673 ADN34674 ADN34675 ADN34676 ADN34677 ADN34678 ADN34679 ADN34680 ADN34681 ADN34682 ADN34683 ADN34684 ADP21921 ADQ75437 ADQ89756 AEQ39730 AEQ54640 AEZ53223 AEZ53224 AFP89334 AGJ50215 AGO06073 AGO06074 AGO06075 AGO06076 BAA11031 BAA11032 BAA11033 BAA11185 BAB63336 BAC54916 BAE78597 BAF31253 CAA43298 CAB46612 EAX03231 EAX03232 EAX03233 EAX03234 EAX03235 EAX03236 P17693 AF071017 AAC25569 AF071018 AAC25570 AF071019 AAC25571 AF071020 AAC25572 AF071021 AAC25573 AF071022 AAC25574 AF196177 AF196178 AF226990 AAF37570 AF436089 AAL30408 AK093478 AK302054 BAG63444 AL551999 AY359818 AAQ83724 BC021708 AAH21708 DC397107 DQ896809 ABM87808 EU176192 ABW03643 M32800 AAA59846 M90683 AAA52673 M90684 AAA59836 M90685 AAA58653 M90686 AAA58654 U58024 AAC04369 U58025 AAC04370 U58026 AAC04371 U58027 AAC04372 U58028 AAC04373 U58029 AAC04374 U58094 AAC04375 U88244 AAD45397 X17273 CAA35174 XM_011547651 XP_011545953 XM_011547882 XP_011546184 XM_011548048 XP_011546350 XM_011548236 XP_011546538 XM_011548237 XP_011546539 XM_011548430 XP_011546732 XM_011548431 XP_011546733 NM_002127 NP_002118 |
| Function | Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in trophoblasts. |
| Top Pathways | Natural killer cell mediated cytotoxicity, Epstein-Barr virus infection, Cell adhesion molecules (CAMs), Viral carcinogenesis, Herpes simplex infection |