| Gene Symbol | CLA1 |
|---|---|
| Entrez Gene | 827230 |
| Alt Symbol | 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE, 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE 2, CLA, CLOROPLASTOS ALTERADOS 1, DEF, DL3821W, DXPS2, DXS, FCAALL.24 |
| Species | Arabidopsis thaliana |
| Gene Type | protein-coding |
| Description | 1-deoxy-D-xylulose-5-phosphate synthase |
| Other Description | - |
| Swissprots | O23407 Q38854 O49738 |
| Accessions | AEE83625 CAB45992 CAB78598 Q38854 BT002340 AAN86173 NM_117647 NP_193291 |
| Function | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). Is a limiting enzyme for plastidic isoprenoid biosynthesis and essential for chloroplast development. {ECO:0000269|PubMed:10982425, ECO:0000269|PubMed:11264287, ECO:0000269|PubMed:8653115}. |
| Subcellular Location | Plastid, chloroplast stroma {ECO:0000305|PubMed:18236010}. |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10982425}. |
| Top Pathways | Terpenoid backbone biosynthesis, Thiamine metabolism |