ACO1

Gene Symbol ACO1
Entrez Gene 48
Alt Symbol ACONS, HEL60, IREB1, IREBP, IREBP1, IRP1
Species Human
Gene Type protein-coding
Description aconitase 1, soluble
Other Description IRE-BP 1|aconitate hydratase, cytoplasmic|citrate hydro-lyase|cytoplasmic aconitate hydratase|epididymis luminal protein 60|ferritin repressor protein|iron regulatory protein 1|iron-responsive element binding protein 1|iron-responsive element-binding protein 1
Swissprots P21399 Q14652 D3DRK7 Q5VZA7
Accessions ABF47095 EAW58549 EAW58550 EAW58551 EAW58552 P21399 AB209480 BAD92717 AF261088 AAF99681 AK057904 AK308752 BC018103 AAH18103 BP287929 BX538349 CAD98144 DA103947 DA409113 DA780353 EU794627 ACJ13681 M58510 AAA69900 Z11559 CAA77651 XM_005251476 XP_005251533 XM_011517888 XP_011516190 NM_001278352 NP_001265281 NM_002197 NP_002188
Function Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding. {ECO:0000269|PubMed:1946430, ECO:0000269|PubMed:8041788}.
Subcellular Location Cytoplasm.
Top Pathways Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Carbon metabolism

ACO1 293T Cell Transient Overexpression Lysate(Denatured) - H00000048-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

ACO1 293 Cell Lysate - 400766 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Aconitase 1 Overexpression Lysate (Denatured) - H00000048-T01 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl
Species Human
ACO1 transfected lysate.

Aconitase 1 Overexpression Lysate (Native) - NBL1-07243 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

IRP-1 (h): 293 Lysate - sc-113248 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

ACO1 Over-expression Lysate Product - GWB-D78818 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Human ACO1 / irp1 Insect Cell Lysate (WB positive control) - 10966-H07BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human ACO1 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175107 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Human

Panoply™ Human ACO1 Knockdown Stable Cell Line - CSC-DC000139 from Creative biogene

Category Cell Line
Species Human
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