GABRA4

Gene Symbol GABRA4
Entrez Gene 2557
Alt Symbol -
Species Human
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor, alpha 4
Other Description GABA(A) receptor, alpha 4|gamma-aminobutyric acid A receptor alpha 4|gamma-aminobutyric acid receptor subunit alpha-4
Swissprots P48169 Q8IYR7
Accessions AAA74743 EAW93029 P48169 AF238869 AK090780 BAG52228 BC035055 AAH35055 BC036474 BC037926 BC042117 BI599812 CD013892 CD013893 DQ891679 ABM82605 DQ894864 ABM85790 EU176605 ABW03406 KJ534840 AHW56480 KJ535037 AHW56676 U30461 AAB52519 XM_011513677 XP_011511979 NM_000809 NP_000800 NM_001204266 NP_001191195 NM_001204267 NP_001191196
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction