GSTM1

Gene Symbol GSTM1
Entrez Gene 2944
Alt Symbol GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1
Species Human
Gene Type protein-coding
Description glutathione S-transferase mu 1
Other Description GST HB subunit 4|GST class-mu 1|HB subunit 4|S-(hydroxyalkyl)glutathione lyase|glutathione S-alkyltransferase|glutathione S-aralkyltransferase|glutathione S-aryltransferase|glutathione S-transferase M1|glutathione S-transferase Mu 1
Swissprots Q8TC98 Q9UC96 Q5GHG0 Q6FH88 P09488
Accessions AAD13938 CAA35817 CAA48636 P09488 AY510272 AAR85979 AY532926 AAT06767 AY532927 AAT06768 BC024005 AAH24005 BC036805 BC095463 BQ436476 CR541868 CAG46666 DB459176 GQ129273 ACT64407 GQ129274 ACT64408 HQ448375 ADQ32855 J03817 AAA59203 KJ534856 AHW56496 KJ534857 AHW56497 KJ534858 AHW56498 KJ534998 AHW56638 KJ535021 AHW56660 X08020 CAA30821 XM_005270782 XP_005270839 XM_005270783 XP_005270840 NM_000561 NP_000552 NM_146421 NP_666533
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000269|PubMed:16548513}.
Subcellular Location Cytoplasm.
Tissue Specificity Liver (at protein level). {ECO:0000269|PubMed:7822249}.
Top Pathways Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450