TTC37

Gene Symbol TTC37
Entrez Gene 9652
Alt Symbol KIAA0372, Ski3, THES
Species Human
Gene Type protein-coding
Description tetratricopeptide repeat domain 37
Other Description SKI3 homolog|TPR repeat protein 37|tetratricopeptide repeat protein 37|thespin|tricho-hepatic-enteric syndrome protein
Swissprots O15077 Q6PGP7 Q6PJI3
Accessions EAW96037 EAW96038 Q6PGP7 AB002370 BAA20827 AK307531 BC009767 BC015163 AAH15163 BC030966 BC056893 AAH56893 XR_948312 NM_014639 NP_055454
Function Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C).
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16024656}. Nucleus {ECO:0000269|PubMed:16024656}.
Tissue Specificity Widely expressed with the highest levels observed in vascular tissues, lymph node, pituitary, lung and intestine. Not expressed in the liver. {ECO:0000269|PubMed:21120949}.
Top Pathways RNA degradation