| Gene Symbol | AQP4 |
|---|---|
| Entrez Gene | 361 |
| Alt Symbol | HMIWC2, MIWC |
| Species | Human |
| Gene Type | protein-coding |
| Description | aquaporin 4 |
| Other Description | WCH4|aquaporin 4 isoform delta4|aquaporin type4|aquaporin-4|mercurial-insensitive water channel |
| Swissprots | P78564 P55087 |
| Accessions | AAG17964 EAX01228 EAX01229 P55087 AB128929 BAD22823 AB209156 BAD92393 AK026728 AK222684 BAD96404 AK295069 BAG58116 AL119338 AL138136 AV725241 BC022286 AAH22286 BC030745 BC045780 BI596912 BI667387 BI917845 BQ638704 CD105892 CK001094 D63412 BAA09715 HQ447648 ADQ32133 HQ901095 ADZ13511 KF055862 AGX27825 N50070 R35726 U34845 AAC50284 U63622 AAB26957 U63623 AAB26958 XM_011525942 XP_011524244 NM_001650 NP_001641 NM_004028 NP_004019 |
| Function | Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Brain - muscle >> heart, kidney, lung, and trachea. |
| Top Pathways | Vasopressin-regulated water reabsorption, Bile secretion |