XRCC1

Gene Symbol XRCC1
Entrez Gene 7515
Alt Symbol RCC
Species Human
Gene Type protein-coding
Description X-ray repair complementing defective repair in Chinese hamster cells 1
Other Description DNA repair protein XRCC1|X-ray repair cross-complementing protein 1
Swissprots Q9HCB1 Q6IBS4 P18887
Accessions AAG09061 AAM34791 AGB76026 AGI15891 AGI15892 AGI15893 AHC92541 EAW57201 EAW57202 EAW57203 P18887 AB208781 BAD92018 AK293542 BAG57023 AK300163 BAG61945 AK315332 BAG37732 BC023593 AAH23593 BP349667 CR456728 CAG33009 M36089 AAA63270 NM_006297 NP_006288
Function Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
Subcellular Location Nucleus {ECO:0000269|PubMed:17353262}. Note=Accumulates at sites of DNA damage.
Top Pathways Base excision repair