ABCC2

Gene Symbol ABCC2
Entrez Gene 1244
Alt Symbol ABC30, CMOAT, DJS, MRP2, cMRP
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Other Description canalicular multidrug resistance protein|canalicular multispecific organic anion transporter 1|multidrug resistance-associated protein 2
Swissprots B2RMT8 Q92798 Q92500 Q5T2B1 Q14022 Q99663 Q9UMS2 Q92887
Accessions AAD47599 CAB45309 CAJ33679 CAS97349 EAW49852 EAW49853 Q92887 BC136419 AAI36420 BM765259 CB120555 U49248 AAB09422 U63970 AAB39892 U66683 X96395 CAA65259 XM_006717630 XP_006717693 XM_006717631 XP_006717694 XM_011539291 XP_011537593 XR_945604 XR_945605 NM_000392 NP_000383
Function Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:11093739}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:11093739}.
Tissue Specificity Expressed by polarized cells in liver, kidney and intestine. The highest expression is found in liver.
Top Pathways ABC transporters, Bile secretion

MRP2/ABCC2 (R260) Antibody - 4446 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using MRP2/ABCC2 (R260) Antibody.

MRP2/ABCC2 (D9F9E) Rabbit mAb - 12559 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9F9E
Western blot analysis of extracts from Hep G2 and A-204 cells using MRP2/ABCC2 (D9F9E) Rabbit mAb.

MRP (E-19) - sc-28288 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MRP (K-19) - sc-28289 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MRP2 (H-17) - sc-5770 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MRP2 (H-17): sc-5770. Western blot analysis of MRP2 expression in A549 whole cell lysate.

MRP2 (H-300) - sc-20766 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MRP2 (M2I-4) - sc-59609 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl supernatant
Host Mouse
Clonality Monoclonal
MRP2 (M2I-4): sc-59609. Western blot analysis of MRP2 expression in JAR (A) and A-431 (B) whole cell lysates.

MRP2 (M2 III-6) - sc-59608 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl supernatant
Host Mouse
Clonality Monoclonal

MRP2 (M2III-5) - sc-59611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl supernatant
Host Mouse
Clonality Monoclonal

MRP2 (6D564) - sc-71603 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl supernatant
Host Mouse
Clonality Monoclonal
MRP2 (6D564): sc-71603. Western blot analysis of MRP2 expression in JAR (A) and A-431 (B) whole cell lysates.

Anti-MRP2 antibody - ab203397 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MRP2 antibody - ab135889 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MRP2 antibody (ab135889) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-MRP2 antibody [EPR10997(2)] - ab187644 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10997(2)
Immunohistochemistry analysis of paraffin-embedded Human liver tissue labeling MRP2 with ab187644 at 1/1000 dilution. A prediluted HRP polymer for Rabbit IgG used as secondary antibody. Counterstained with Hematoxylin.

Anti-MRP2 antibody [EPR10998] - ab172630 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10998
Flow cytometric analysis of permeabilized A549 cells using ab172630 at a 1/100 dilution (red) or a rabbit IgG (negative) (green).

Anti-MRP2 antibody [M2 III-6] - ab3373 from Abcam

Prices $392.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone M2 III-6
ab3373 at 1/200 staining rat liver tissue sections by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). The tissue was formaldehyde fixed and then heat mediated antigen retrieval was performed using citrate buffer. The antibody was incubated with the tissue for 1 hour. An HRP conjugated goat anti-mouse antibody was used as the secondary.See Abreview

Anti-MRP2 antibody [M2I-4] - ab3372 from Abcam

Host Mouse
Clonality Monoclonal
Clone M2I-4

Anti-MRP2 antibody [M2II-12] - ab24106 from Abcam

Prices $372.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone M2II-12

Anti-MRP2 antibody [M2II-12] - ab130385 from Abcam

Host Mouse
Clonality Monoclonal
Clone M2II-12

Anti-MRP2 antibody [M2III-5] - ab15603 from Abcam

Prices $378.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone M2III-5

Anti-ABCC2 / MRP2 Antibody (aa825-875) - LS-C291056 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human ABCC2 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) prepared using NETN buffer from HepG2 cells. Antibodies: Affinity purified rabbit anti-ABCC2 antibody used for IP at 6 ug per reaction. ABCC2 was also immunoprecipitated by rabbit anti-ABCC2 antibody BL15953. For blotting immunoprecipitated ABCC2, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-ABCC2 / MRP2 Antibody (clone 1C5) - LS-C196939 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C5
Detection limit for recombinant GST tagged ABCC2 is approximately 0.03 ng/ml as a capture antibody.

Anti-ABCC2 / MRP2 Antibody - LS-C178463 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCC2 / MRP2 Antibody (aa977-1026) IHC-plus™ - LS-B10445 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ABCC2 / MRP2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10445 concentration 5 ug/ml.

Anti-ABCC2 / MRP2 Antibody (aa1339-1541) - LS-C16474 from LifeSpan Bioscience

Prices $560.00
Sizes 125 µg
Host Mouse
Clonality Monoclonal

Anti-ABCC2 Antibody - LS-C72796 from LifeSpan Bioscience

Prices $530.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Search more