C8B

Gene Symbol C8B
Entrez Gene 732
Alt Symbol C82
Species Human
Gene Type protein-coding
Description complement component 8, beta polypeptide
Other Description complement component 8 subunit beta|complement component C8 beta chain
Swissprots A1L4K7 P07358
Accessions EAX06641 EAX06642 EAX06643 P07358 AK292740 BAF85429 AK298425 BAH12786 AK298444 BAH12791 AK313382 BAG36180 AK316209 BAH14580 BC020701 AAH20701 BC130575 AAI30576 CD364465 HQ258464 ADR83218 M16973 AAA51862 X04393 CAA27981 NM_000066 NP_000057 NM_001278543 NP_001265472 NM_001278544 NP_001265473
Function Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis