| Gene Symbol | OGG1 |
|---|---|
| Entrez Gene | 4968 |
| Alt Symbol | HMMH, HOGG1, MUTM, OGH1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | 8-oxoguanine DNA glycosylase |
| Other Description | 8-hydroxyguanine DNA glycosylase|AP lyase|DNA-apurinic or apyrimidinic site lyase|N-glycosylase/DNA lyase|OGG1 type 1f |
| Swissprots | Q9Y6C3 Q9BW42 O95488 Q9Y6C4 O00705 O14876 A8K1E3 Q9Y2C1 O15527 O00390 P78554 Q9UL34 O00670 Q9UIK0 Q9Y2C0 Q9UIK1 Q9UIK2 |
| Accessions | AAD41680 AAD41681 AAD41682 AAM74236 ADQ20117 ADQ20118 ADQ20119 ADQ20120 ADQ20121 ADQ20122 ADQ20123 ADQ20124 ADQ20125 ADQ20126 ADQ20127 ADQ20128 ADQ20129 ADQ20130 ADQ20131 ADQ20132 ADQ20133 ADQ20134 ADQ20135 ADQ20136 ADQ20137 ADQ20138 ADQ20139 ADQ20140 ADQ20141 ADQ20142 ADQ20143 ADQ20144 ADQ20145 ADQ20146 ADQ20147 ADQ20148 ADQ20149 ADQ20150 ADQ20151 ADQ20152 ADQ20153 ADQ20154 ADQ20155 ADQ20156 ADQ20157 ADQ20158 ADQ20159 ADQ20160 ADQ20161 ADQ20162 ADQ20163 ADQ20166 ADQ20167 ADQ20168 ADQ20169 ADQ20170 ADQ20171 ADQ20172 ADQ20173 ADQ20174 ADQ20175 ADQ20176 ADQ20177 ADQ20178 ADQ20179 ADQ20180 ADQ20181 ADQ20182 ADQ20183 ADQ20184 ADQ20185 ADQ20186 ADQ20187 ADQ20188 ADQ20189 ADQ20190 ADQ20191 ADQ20192 ADQ20193 ADQ20194 ADQ20195 ADQ20196 ADQ20197 ADQ20198 ADQ20199 ADQ20200 ADQ20201 ADQ20202 ADQ20203 ADQ20204 ADQ20205 ADQ20206 ADQ20207 ADQ20208 ADQ20209 ADQ20210 ADQ20211 ADQ20212 ADQ20215 ADQ20216 ADQ20217 ADQ20218 ADQ20219 ADQ20220 ADQ20221 ADQ20222 ADQ20223 ADQ20224 ADQ20225 ADQ20226 ADQ20227 ADQ20228 ADQ20229 ADQ20230 ADQ20231 ADQ20232 ADQ20233 ADQ20234 ADQ20235 ADQ20236 ADQ20237 ADQ20238 ADQ20239 ADQ20240 ADQ20241 ADQ20242 ADQ20243 ADQ20244 ADQ20245 ADQ20246 ADQ20247 ADQ20250 ADQ20251 ADQ20252 ADQ20253 ADQ20254 ADQ20257 ADQ20258 ADQ20259 ADQ20260 ADQ20261 ADQ20262 ADQ20263 ADQ20264 ADQ20265 ADQ20266 ADQ20267 ADQ20268 ADQ20269 ADQ20270 ADQ20271 ADQ20272 ADQ20273 ADQ20274 ADQ20275 ADQ20276 ADQ20277 ADQ20278 ADQ20279 ADQ20280 ADQ20281 ADQ20282 ADQ20283 ADQ20284 ADQ20285 ADQ20286 ADQ20287 ADQ20288 ADQ20289 ADQ20290 ADQ20291 ADQ20292 ADQ20293 ADQ20294 ADQ20295 ADQ20296 ADQ20297 ADQ20298 ADQ20299 ADQ20300 ADQ20301 ADQ20302 ADQ20303 ADQ20304 ADQ20305 ADQ20306 ADQ20307 ADQ20308 ADQ20309 ADQ20310 ADQ20311 ADQ20312 ADQ20313 ADQ20314 ADQ20315 ADQ20316 ADQ20317 ADQ20318 ADQ20319 ADQ20320 ADQ20321 ADQ20322 ADQ20323 ADQ20324 ADQ20325 ADQ20326 ADQ20327 ADQ20328 ADQ20329 ADQ20330 ADQ20331 ADQ20332 ADQ20333 ADQ20334 ADQ20335 ADQ20336 ADQ20337 ADQ20338 ADQ20339 ADQ20340 ADQ20341 ADQ20342 ADQ20343 ADQ20344 ADQ20345 ADQ20346 ADQ20347 ADQ20348 ADQ20349 ADQ20350 ADQ20351 ADQ20352 ADQ20353 ADQ20354 ADQ20355 ADQ20356 ADQ20357 ADQ20358 ADQ20359 ADQ20360 ADQ20361 ADQ20362 ADQ20363 ADQ20364 ADQ20365 ADQ20366 ADQ20367 ADQ20368 ADQ20369 ADQ20370 ADQ20371 ADQ20372 ADQ20373 ADQ20374 ADQ20375 ADQ20376 ADQ20377 ADQ20378 ADQ20379 ADQ20380 ADQ20381 ADQ20382 ADQ20383 ADQ20384 ADQ20385 ADQ20386 ADQ20387 ADQ20388 ADQ20389 ADQ20390 ADQ20391 ADQ20392 ADQ20393 ADQ20394 ADQ20395 ADQ20396 CAA10351 EAW63978 EAW63979 EAW63980 EAW63981 EAW63982 EAW63983 EAW63984 EAW63985 EAW63986 EAW63987 EAW63988 O15527 AB000410 BAA19103 AB019528 BAA76635 AB019529 BAA76636 AB019530 BAA76637 AB019531 BAA76638 AB019532 BAA76639 AB037878 BAB13293 AB037879 BAB13294 AB037880 BAB13295 AB037881 BAB13296 AB037882 BAB13297 AF003595 AAB61340 AF026691 AAB84013 AK289858 BAF82547 AW614399 BC000657 AAH00657 BM847736 DQ896107 ABM87106 EU176392 ABW03843 U88527 AAB68614 U88620 AAB68615 U96710 AAB81132 Y11731 CAA72414 Y11838 CAA72536 Y13277 CAA73726 XM_011533760 XP_011532062 XM_011533761 XP_011532063 NM_002542 NP_002533 NM_016819 NP_058212 NM_016820 NP_058213 NM_016821 NP_058214 NM_016826 NP_058434 NM_016827 NP_058436 NM_016828 NP_058437 NM_016829 NP_058438 |
| Function | DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion. |
| Subcellular Location | Isoform 2A: Mitochondrion. |
| Tissue Specificity | Ubiquitous. |
| Top Pathways | Base excision repair |