MAOA

Gene Symbol MAOA
Entrez Gene 100033867
Alt Symbol -
Species Horse
Gene Type protein-coding
Description monoamine oxidase A
Other Description MAO-A|amine oxidase [flavin-containing] A|monoamine oxidase type A
Swissprots Q5NU32
Accessions Q5NU32 AB178282 BAD80721 NM_001081832 NP_001075301
Function Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion outer membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Top Pathways Glycine, serine and threonine metabolism, Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism