INPP4A

Gene Symbol INPP4A
Entrez Gene 3631
Alt Symbol INPP4, TVAS1
Species Human
Gene Type protein-coding
Description inositol polyphosphate-4-phosphatase, type I, 107kDa
Other Description inositol polyphosphate-4-phosphatase, type I, 107kD|type I inositol 3,4-bisphosphate 4-phosphatase|type I inositol-3,4-bisphosphate 4-phosphatase
Swissprots Q53TD8 Q8TC02 Q96PE3 Q13187 O15326
Accessions AAX93230 EAX01904 EAX01905 EAX01906 EAX01907 EAX01908 EAX01909 EAX01910 Q96PE3 AB462500 AF368319 AAK58870 AK057550 AK091533 AK307823 BC005082 BC028361 AAH28361 DQ895315 ABM86241 U26398 AAB01068 U96919 AAB72150 XM_006712499 XP_006712562 XM_006712500 XP_006712563 XM_006712501 XP_006712564 XM_006712502 XP_006712565 XM_006712503 XP_006712566 XM_006712504 XP_006712567 XM_006712505 XP_006712568 XM_006712506 XP_006712569 XM_006712507 XP_006712570 XM_006712508 XP_006712571 XM_011511122 XP_011509424 XM_011511123 XP_011509425 XM_011511124 XP_011509426 XM_011511125 XP_011509427 XM_011511126 XP_011509428 XM_011511127 XP_011509429 XR_922915 XR_922916 NM_001134224 NP_001127696 NM_001134225 NP_001127697 NM_001566 NP_001557 NM_004027 NP_004018
Function Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate.
Tissue Specificity Isoform 1 is expressed in the platelets, MEG- 01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain. {ECO:0000269|PubMed:11485317}.
Top Pathways Inositol phosphate metabolism, Phosphatidylinositol signaling system