| Gene Symbol | INPP5A |
|---|---|
| Entrez Gene | 3632 |
| Alt Symbol | 5PTASE |
| Species | Human |
| Gene Type | protein-coding |
| Description | inositol polyphosphate-5-phosphatase, 40kDa |
| Other Description | 43 kDa inositol polyphosphate 5-phophatase|CTCL tumor antigen HD-CL-02|InsP3 5-phosphatase|inositol polyphosphate-5-phosphatase, 40kD|inositol trisphosphate-5-phosphatase, 40kD|type I inositol 1,4,5-trisphosphate 5-phosphatase|type I inositol-1,4,5-trisphosphate 5-phophatase|type I inositol-1,4,5-trisphosphate 5-phosphatase |
| Swissprots | Q14642 Q14640 Q5JSF1 D3DXI3 |
| Accessions | AAK13252 EAW61306 EAW61307 Q14642 AF273055 AAM44458 BC052265 AAH52265 BC062300 AAH62300 BC096280 AAH96280 BC096281 AAH96281 BC117515 AAI17516 BM467443 BM666428 CB960907 X77567 CAA54676 Z31695 CAA83500 XM_011539768 XP_011538070 XR_945735 NM_005539 NP_005530 |
| Function | Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. |
| Subcellular Location | Membrane; Lipid-anchor. |
| Tissue Specificity | Brain; high level in Purkinje cells. |
| Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |