Dao

Gene Symbol Dao
Entrez Gene 100689280
Alt Symbol DAAO, DAMOX
Species Hamster
Gene Type protein-coding
Description D-amino-acid oxidase
Other Description D-amino acid oxidase
Swissprots Q9Z302
Accessions BAA74715 Q9Z302 XM_007609005 XP_007607195 XM_007609006 XP_007607196 XM_007644135 XP_007642325 XM_007644136 XP_007642326 NM_001244409 NP_001231338
Function Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). {ECO:0000250}.
Subcellular Location Peroxisome {ECO:0000250}.
Top Pathways Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism