| Gene Symbol | iki3 |
|---|---|
| Entrez Gene | 2541017 |
| Alt Symbol | - |
| Species | S. pombe |
| Gene Type | protein-coding |
| Description | elongator subunit Iki3 (predicted) |
| Other Description | - |
| Swissprots | O59704 |
| Accessions | CAA19055 O59704 NM_001021243 NP_595335 |
| Function | Acts as component of the RNA polymerase II elongator complex, which is a major histone acetyltransferase component of the RNA polymerase II (RNAPII) holoenzyme and is involved in transcriptional elongation. Association with elongating RNAPII requires a hyperphosphorylated state of the RNAPII C-terminal domain (CTD). Elongator binds to both naked and nucleosomal DNA, can acetylate both core and nucleosomal histones, and is involved in chromatin remodeling (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16823372}. |