CSH1

Gene Symbol CSH1
Entrez Gene 1442
Alt Symbol CS-1, CSA, CSMT, PL, hCS-1, hCS-A
Species Human
Gene Type protein-coding
Description chorionic somatomammotropin hormone 1 (placental lactogen)
Other Description choriomammotropin|chorionic somatomammotropin A|chorionic somatomammotropin hormone 1|chorionic somatomammotropin-1|placental lactogen
Swissprots Q14407 Q0VDB1 P01243 P0DML2
Accessions AAA52115 AAA52551 AAO64720 ABZ88716 ABZ88717 ABZ88718 CBH19248 EAW94235 EAW94236 EAW94237 EAW94241 EAW94243 EAW94254 EAW94257 EAW94259 P0DML2 AK291587 BAF84276 AU134786 BC002717 AAH02717 BC005921 AAH05921 BC020756 AAH20756 BC057768 AAH57768 BC062775 AAH62775 BG436049 BQ004002 BT006926 AAP35572 HQ447195 ADQ31682 J00118 AAA98621 M25118 AAA35721 M35419 AAP03711 V00593 CAA23840 NM_001317 NP_001308 NM_022640 NM_022641
Function Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. {ECO:0000269|PubMed:16546209}.
Subcellular Location Secreted.
Top Pathways Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction