| Gene Symbol | TUBB |
|---|---|
| Entrez Gene | 203068 |
| Alt Symbol | CDCBM6, M40, OK/SW-cl.56, TUBB1, TUBB5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | tubulin, beta class I |
| Other Description | beta Ib tubulin|tubulin beta chain|tubulin beta-1 chain|tubulin beta-5 chain|tubulin, beta polypeptide |
| Swissprots | P07437 Q8WUC1 Q9CY33 P05218 |
| Accessions | AAB59507 BAB63321 BAC54932 BAE78618 BAF31267 EAX03322 EAX03323 EAX03324 P07437 AB062393 BAB93480 AF070561 AAC28642 AF070593 AAC28650 AF070600 AAC28654 AF141349 AAD33873 AK098772 AK297489 BAG59907 AK297638 BAG60010 AK298889 BAG61001 AK302195 BAG63557 AK302314 BAG63652 AK303227 BAG64314 AK309684 AK316265 BAH14636 AK316316 BAH14687 BC001002 BC001896 AAH01896 BC001938 AAH01938 BC002347 AAH02347 BC005838 AAH05838 BC007605 AAH07605 BC013374 AAH13374 BC015889 AAH15889 BC019924 AAH19924 BC020946 AAH20946 BC021909 AAH21909 BC029323 BC062532 AAH62532 BC070326 AAH70326 BC103746 AAI03747 BE245819 BQ019614 BU557299 DC353572 DC366174 DC389555 DC405540 DQ457058 ABE96641 DQ891742 ABM82668 DQ891828 ABM82754 DQ894920 ABM85846 EF036509 ABO65095 V00599 CAA23844 Z36874 NM_001293212 NP_001280141 NM_001293213 NP_001280142 NM_001293214 NP_001280143 NM_001293215 NP_001280144 NM_001293216 NP_001280145 NM_178014 NP_821133 NR_120608 |
| Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
| Subcellular Location | Cytoplasm, cytoskeleton. |
| Tissue Specificity | Ubiquitously expressed with highest levels in spleen, thymus and immature brain. {ECO:0000269|PubMed:20191564}. |
| Top Pathways | Gap junction, Pathogenic Escherichia coli infection, Phagosome |