vps46

Gene Symbol vps46
Entrez Gene 8616449
Alt Symbol DDBDRAFT_0189855, DDBDRAFT_0191317, DDB_0189855, DDB_0191317
Species Dictyostelium discoideum
Gene Type protein-coding
Description SNF7 family protein
Other Description -
Swissprots Q55F99 O96552
Accessions EAL73149 XM_642542 XP_647634
Function Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). {ECO:0000250}.
Subcellular Location Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Top Pathways Endocytosis