dnaA

Gene Symbol dnaA
Entrez Gene 7124611
Alt Symbol -
Species Escherichia coli
Gene Type protein-coding
Description chromosomal replication initiation protein
Other Description -
Swissprots B7M553
Accessions B7M553 CAR00675 YP_002389181
Function Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
Top Pathways Two-component system