| Gene Symbol | entF |
|---|---|
| Entrez Gene | 945184 |
| Alt Symbol | ECK0579, JW0578 |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | enterobactin synthase multienzyme complex component, ATP-dependent |
| Other Description | - |
| Swissprots | P75723 P11454 P77095 Q2MBL5 |
| Accessions | AAC73687 NP_415118 |
| Function | Activates the carboxylate group of L-serine via ATP- dependent PPi exchange reactions to the aminoacyladenylate, preparing that molecule for the final stages of enterobactin synthesis. Holo-EntF acts as the catalyst for the formation of the three amide and three ester bonds present in the cyclic (2,3- dihydroxybenzoyl)serine trimer enterobactin, using seryladenylate and acyl-holo-EntB (acylated with 2,3-dihydroxybenzoate by EntE). |
| Top Pathways | Biosynthesis of siderophore group nonribosomal peptides |