Txnrd2

Gene Symbol Txnrd2
Entrez Gene 26462
Alt Symbol AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2
Species Mouse
Gene Type protein-coding
Description thioredoxin reductase 2
Other Description TR beta|thioredoxin reductase 2, mitochondrial|thioredoxin reductase TR3
Swissprots Q91YX4 Q9JMH5 Q9JHA7 Q80VZ4 Q6KG49 Q9JLT4
Accessions AAL90457 EDK97524 EDK97525 EDK97526 Q9JLT4 AB027566 BAA86986 AF136399 AAF03359 AF171053 AAD51323 AF412308 AAQ03230 AK008004 BAB25403 AK075828 AK181417 AK186982 AK188250 BC013688 AAH13688 BC029344 BC052157 AAH52157 BC052758 BF465261 NM_013711 NP_038739
Function Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:10721726}.
Tissue Specificity Expressed in liver, heart, testis and kidney. {ECO:0000269|PubMed:10455115, ECO:0000269|PubMed:10500251, ECO:0000269|PubMed:10721726}.
Top Pathways Selenocompound metabolism, Pyrimidine metabolism