| Gene Symbol | pldC |
|---|---|
| Entrez Gene | 8621238 |
| Alt Symbol | DDBDRAFT_0204320, DDBDRAFT_0231508, DDB_0204320, DDB_0231508 |
| Species | Dictyostelium discoideum |
| Gene Type | protein-coding |
| Description | phospholipase D1 |
| Other Description | - |
| Swissprots | Q54Z25 |
| Accessions | EAL68147 XM_636935 XP_642027 |
| Function | Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho (phosphatidylcholine), producing the free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization. {ECO:0000269|PubMed:15769249, ECO:0000269|PubMed:6498208, ECO:0000269|PubMed:8394342}. |
| Top Pathways | Endocytosis, Ether lipid metabolism, Glycerophospholipid metabolism |