Gene Symbol |
stt3
|
Entrez Gene |
2540190
|
Alt Symbol |
-
|
Species |
S. pombe
|
Gene Type |
protein-coding
|
Description |
oligosaccharyltransferase subunit Stt3
|
Other Description |
-
|
Swissprots |
Q8WZK7 O94335
|
Accessions |
CAA22192 O94335 NM_001021056 NP_595148
|
Function |
Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER) (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
Top Pathways |
N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis
|