| Gene Symbol | nfsB |
|---|---|
| Entrez Gene | 945778 |
| Alt Symbol | ECK0570, JW0567, dprA, nfnB, nfsI, ntr |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | dihydropteridine reductase, NAD(P)H-dependent, oxygen-insensitive |
| Other Description | - |
| Swissprots | P38489 P19575 |
| Accessions | AAC73679 NP_415110 |
| Function | Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5- (aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species. {ECO:0000269|PubMed:15684426}. |
| Top Pathways | Nitrotoluene degradation |