Recombinant Human NKG2D Fc Chimera, CF

• Supplier: R&D Systems
• Catalog: 1299-NK-050
• Category: Protein
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: P26718
• Gene: KLRK1

Product References

Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone - Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone

Leung WH, Vong QP, Lin W, Janke L, Chen T, Leung W. J Exp Med. 2013 Nov 18;210(12):2675-92.

Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells. - Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells.

Bellucci R, Nguyen HN, Martin A, Heinrichs S, Schinzel AC, Hahn WC, Ritz J. J Clin Invest. 2012 Jul;122(7):2369-83.

Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role - Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role

Inagaki A, Ishida T, Yano H, Ishii T, Kusumoto S, Ito A, Ri M, Mori F, Ding J, Komatsu H, Iida S, Ueda R. Int J Cancer. 2009 Jul 1;125(1):212-21.

Generation, affinity maturation, and characterization of a human anti-human NKG2D - Generation, affinity maturation, and characterization of a human anti-human NKG2D

Kwong KY, Baskar S, Zhang H, Mackall CL, Rader C. J Mol Biol. 2008 Dec 31;384(5):1143-56.

The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated - The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated

El-Sherbiny YM, Meade JL, Holmes TD, McGonagle D, Mackie SL, Morgan AW, Cook G, Feyler S, Richards SJ, Davies FE, Morgan GJ, Cook GP. Cancer Res. 2007 Sep 15;67(18):8444-9.

HIV modulates the expression of ligands important in triggering natural killer - HIV modulates the expression of ligands important in triggering natural killer

Ward J, Bonaparte M, Sacks J, Guterman J, Fogli M, Mavilio D, Barker E. Blood. 2007 Aug 15;110(4):1207-14. Epub 2007 May 18.

Human T-cell leukemia virus type 1 (HTLV-1) p12I down-modulates ICAM-1 and -2 and - Human T-cell leukemia virus type 1 (HTLV-1) p12I down-modulates ICAM-1 and -2 and

Banerjee P, Feuer G, Barker E. J Virol. 2007 Sep;81(18):9707-17. Epub 2007 Jul 3.

A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural - A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural

von Strandmann EP, Hansen HP, Reiners KS, Schnell R, Borchmann P, Merkert S, Simhadri VR, Draube A, Reiser M, Purr I, Hallek M, Engert A. Blood. 2006 Mar 1;107(5):1955-62. Epub 2005 Oct 6.

Cancer cells become susceptible to natural killer cell killing after exposure to - Cancer cells become susceptible to natural killer cell killing after exposure to

Skov S, Pedersen MT, Andresen L, Straten PT, Woetmann A, Odum N. Cancer Res. 2005 Dec 1;65(23):11136-45.

BCR/ABL promotes dendritic cell-mediated natural killer cell activation. - BCR/ABL promotes dendritic cell-mediated natural killer cell activation.

Terme M, Borg C, Guilhot F, Masurier C, Flament C, Wagner EF, Caillat-Zucman S, Bernheim A, Turhan AG, Caignard A, Zitvogel L. Cancer Res. 2005 Jul 15;65(14):6409-17.