| Description |
GH-20K protein.Placental growth hormone, or growth hormone variant(GH-V), is a member of the growth hormone gene family.Its physiologic role during pregnancy remains undefined.Although extensive work has been done characterizingthe signaling pathways activated by hGH, the signalingpathways which are activated by GH-V have not beencharacterized.Human placental GH (hPGH) replaces pituitary GH duringpregnancy. hPGH is correlated to serum IGF-I in normalpregnancies and in pregnancies complicated by fetoplacental disorders.Recombinant Placental Human GH-20K produced inE. coli is a single, non-glycosylated, polypeptide chaincontaining 177 amino acids and having a molecular massof 20.5 kDa. GH-20K is devoid of lactogenic (prolactin receptor mediated) activity characteristic to pituitary GHs.Placental Growth Hormone is purified by proprietary chromatographic techniques.
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