Rat MIP-1 beta protein

• Supplier: Biorbyt
• Catalog: orb107785
• Category: Protein
• Prices: $264.00, $357.00, $629.00, $1,046.00, $1,751.00, $2,865.00
• Sizes: 5 μg, 20 μg, 100 μg, 250 μg, 500 μg, 1 mg
• Applications: SDS-PAGE HPLC
• Species Reactivities: Rat
• Nature: Recombinant
• Source: E.coli
• Purity: > 95% by SDS-PAGE and HPLC analyses
• Gene: CCL4L2
• Sequence: APIGSDPPTS CCFSYTSRKI HRNFVMDYYE TSSLCSQPAV VFLTKKGRQI CADPSEPWVNEYVNDLELN
• Description: Recombinant Rat Macrophage Inflammatory Protein-1 beta/CCL4. Chemokine (C-C motif) ligand 4 encoded by the CCL4 gene, also known as macrophage inflammatory protein-1beta (MIP-1beta) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. Recombinant CCL4 induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). Furthermore, recombinant rat CCL4 contains 69 amino acids and it shares 80 % and 86 % a.a. sequence identity with human and murine CCL4. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.