UROS, 1-265aa, Human, His tag, E.coli

Name UROS, 1-265aa, Human, His tag, E.coli
Supplier ARP American Research Products
Catalog 01-P1066
Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Applications SDS-PAGE
Species Reactivities Human
Nature Recombinant
Purity > 95% by SDS - PAGE
Gene UROS
Sequence MGSSHHHHHH SSGLVPRGSH MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSG LTYSLKHIQE LSGDNIDQIK FAAIGPTTAR ALAAQGLPVS CTAESPTPQA LATGIRKALQ PHGCC
Description UROS, also known as Uroporphyrinogen III synthase, is an enzyme involved in the fourth step of porphyrin metabolism, involved in the conversion of hydroxymethyl bilane into uroporphyrinogen III. Defects in this protein can cause molecular lesions that lead to the autosomal recessive Gunther disease, also known as congenital erythropoietic porphyria (CEP)
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