| Name | Mouse MCSF |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 600202 |
| Category | Protein |
| Prices | $250.00 |
| Sizes | 10 µg |
| Species Reactivities | Mouse |
| Source | E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug. |
| Purity | Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
| Bioactivity | Recombinant mouse M-CSF is fully biologically active when compared to standards. The ED50, as determined by dose-dependent induction of M-NFS-60 cell proliferation, is 0.91 ng/ml. |
| Gene | Csf1 |
| Sequence | MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP |
| Description | Macrophage colony-stimulating Factor 1 (M-CSF) is produced by a wide variety of cells including fibroblasts, monocytes, lymphocytes, osteoblasts, and mesenchymal cells. It stimulates the proliferation and differentiation of hematopoietic cells and plays an important role in the life of blood monocytes. M-CSF is comprised of two 159 amino acid chains, the disulfide-linked homodimer has a MW of 36.8 kDa |
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