| Name | Mouse IL-31 |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 600372 |
| Category | Protein |
| Prices | $250.00 |
| Sizes | 10 µg |
| Species Reactivities | Mouse |
| Nature | Recombinant |
| Source | E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug. |
| Purity | Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
| Bioactivity | The activity is determined by the dose dependent production of IL-8 from human PBMCs and is typically less than 25 ng/mL. Specific activity: 4 x 10e4 units/mg |
| Gene | Il31 |
| Sequence | MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C |
| Description | Interleukin-31 (IL-31) is an immunoregulatory cytokine that is mainly expressed by activated TH2 cells. IL-31 signals through the IL-31 Receptor (IL-31RA) and the oncostain receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 has a role in inflammatory skin diseases.Mouse IL-31 is produced in E.coli. Recombinant mouse IL-31 is a non-glycosylated protein, containing 141 amino acids, with a molecular weight of 15.7 kDa. |
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