CFTR Peptide

• Supplier: ABBIOTEC
• Catalog: 350548
• Category: Peptide
• Prices: $50.00
• Sizes: 100 µg
• Purity: Purity > 80% by HPLC
• Gene: CFTR
• Sequence: The synthetic peptide used to raise the antibody Cat. No. 200186 is selected from a sequence within the N-term region of human CFTR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
• Description: Cystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis.