Recombinant Human Cathepsin C/DPPI Protein, CF
| Name | Recombinant Human Cathepsin C/DPPI Protein, CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 1071-CY |
| Category | Protein |
| Prices | $329.00, $36,600.00 |
| Sizes | 10 µg, 10 µg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | Mouse myeloma cell line, NS0-derived Asp25-Leu463, with a C-terminal 10-His tag |
| Purity | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain |
| Bioactivity | Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Arg-7-amido-4-methylcoumarin (GR-AMC). The specific activity is >200 pmol/min/µg, as measured under the described conditions. See Activity Assay Protocol on www.RnDSystems.com |
| Endotoxin | <1.0 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | P53634 |
| Gene | CTSC |
| Sequence | Asp25 |
| Supplier Page | Shop |
Product images
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Product References
Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis. - Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis.
Hamilton G, Colbert JD, Schuettelkopf AW, Watts C. EMBO J. 2008 Feb 6;27(3):499-508.
Design of protease-resistant myelin basic protein-derived peptides by cleavage - Design of protease-resistant myelin basic protein-derived peptides by cleavage
Burster T, Marin-Esteban V, Boehm BO, Dunn S, Rotzschke O, Falk K, Weber E, Verhelst SH, Kalbacher H, Driessen C. Biochem Pharmacol. 2007 Nov 15;74(10):1514-23. Epub 2007 Aug 2.
Inhibition of the activation of multiple serine proteases with a cathepsin C - Inhibition of the activation of multiple serine proteases with a cathepsin C
Methot N, Rubin J, Guay D, Beaulieu C, Ethier D, Reddy TJ, Riendeau D, Percival MD. J Biol Chem. 2007 Jul 20;282(29):20836-46. Epub 2007 May 29.
An activity-based probe for the determination of cysteine cathepsin protease - An activity-based probe for the determination of cysteine cathepsin protease
Falgueyret JP, Black WC, Cromlish W, Desmarais S, Lamontagne S, Mellon C, Riendeau D, Rodan S, Tawa P, Wesolowski G, Bass KE, Venkatraman S, Percival MD. Anal Biochem. 2004 Dec 15;335(2):218-27.