Recombinant Mouse Cripto Protein, CF

• Supplier: R&D Systems
• Catalog: 1538-CR/CF
• Category: Protein
• Prices: $329.00
• Sizes: 10 µg
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Mouse Cripto (Arg26-Gln150) Accession # P51865 DI 6-His tag N-terminus C-terminus
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its binding ability in a functional ELISA. Immobilized rmActivin RIB/Fc Chimera at 1 µg/mL (100 µL/well) can bind rmCripto with a linear range of 0.8-100 ng/mL. This protein will also bind rmNodal in a functional ELISA.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: P51865
• Gene: Tdgf1
• Sequence: Arg26

Product References

Role of Cripto-1 during epithelial-to-mesenchymal transition in development and - Role of Cripto-1 during epithelial-to-mesenchymal transition in development and

Rangel MC, Karasawa H, Castro NP, Nagaoka T, Salomon DS, Bianco C. Am J Pathol. 2012 Jun;180(6):2188-200.

Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland. - Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland.

Strizzi L, Mancino M, Bianco C, Raafat A, Gonzales M, Booth BW, Watanabe K, Nagaoka T, Mack DL, Howard B, Callahan R, Smith GH, Salomon DS. J Cell Physiol. 2008 Sep;216(3):824-34.

Canonical Wnt signaling is required for development of embryonic stem - Canonical Wnt signaling is required for development of embryonic stem

Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM. Development. 2006 Oct;133(19):3787-96. Epub 2006 Aug 30.

CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo. - CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo.

Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC. Stem Cell Reports. 2014 Apr 3;2(4):427-39.