Name | Recombinant Mouse LRP-6 Protein, CF |
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Supplier | R&D Systems |
Catalog | 2960-LR |
Category | Protein |
Prices | $329.00 |
Sizes | 25 µg |
Species Reactivities | Mouse |
Nature | Recombinant |
Source | Mouse myeloma cell line, NS0-derived Ala20-Pro1368, with a C-terminal 6-His tag |
Purity | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain |
Bioactivity | Measured by its binding ability in a functional ELISA. rmLRP-6 binds rhDkk-1, biotin with an apparent K D <15 nM. Biotinylated rmWnt-3a immobilized on a streptavidin-coated plate at 1 µg/mL can bind rmLRP-6 with a linear range of 0.2-10 µg/mL. |
Endotoxin | <0.1 EU per 1 μg of the protein by the LAL method. |
SwissProt/Accession | O88572 |
Gene | Lrp6 |
Sequence | Ala20 |
Supplier Page | Shop |
Liu S, Leask A. Mol Biol Cell. 2013 Dec;24(24):3939-44.
Krause C, Korchynskyi O, de Rooij K, Weidauer SE, de Gorter DJ, van Bezooijen RL, Hatsell S, Economides AN, Mueller TD, Lowik CW, ten Dijke P. J Biol Chem. 2010 Dec 31;285(53):41614-26.