Recombinant Mouse sTNF RII/TNFRSF1B Protein

• Supplier: R&D Systems
• Catalog: 426-R2
• Category: Protein
• Prices: $349.00
• Sizes: 50 µg
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: E. coli -derived Val23-Gly258
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Bioactivity: Measured by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED 50 for this effect is 1-3 µg/mL in the presence of 0.1 ng/mL of recombinant mouse TNF-alpha.
• Endotoxin: <0.01 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: Q545P4
• Gene: Tnfrsf1b
• Sequence: Val23

Product References

Soluble TNFRp75 regulates host protective immunity against Mycobacterium - Soluble TNFRp75 regulates host protective immunity against Mycobacterium

Keeton R, Allie N, Dambuza I, Abel B, Hsu NJ, Sebesho B, Randall P, Burger P, Fick E, Quesniaux VF, Ryffel B, Jacobs M. J Clin Invest. 2014 Apr;124(4):1537-51.

Circulating cytokine/inhibitor profiles reshape the understanding of the - Circulating cytokine/inhibitor profiles reshape the understanding of the

Osuchowski MF, Welch K, Siddiqui J, Remick DG. J Immunol. 2006 Aug 1;177(3):1967-74.

Sequential ELISA to profile multiple cytokines from small volumes. - Sequential ELISA to profile multiple cytokines from small volumes.

Osuchowski MF, Siddiqui J, Copeland S, Remick DG. J Immunol Methods. 2005 Jul;302(1-2):172-81.

Selective macrophage suppression during sepsis. - Selective macrophage suppression during sepsis.

Ellaban E, Bolgos G, Remick D. Cell Immunol. 2004 Sep-Oct;231(1-2):103-11. Epub 2005 Feb 26.