Recombinant Mouse OX40 Ligand/TNFSF4 Protein

• Supplier: R&D Systems
• Catalog: 1236-OX
• Category: Protein
• Prices: $329.00
• Sizes: 25 µg
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Gln49-Leu198, with an N-terminal 10-His tag
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its ability to co-stimulate IL-2 secretion by mouse T cells in the presence of anti-CD3. The ED 50 for this effect is 10-30 ng/mL in the presence of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ).
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: P43488
• Gene: Tnfsf4
• Sequence: His

Product References

Highly reduced binding to high and low affinity mouse Fc gamma receptors by - Highly reduced binding to high and low affinity mouse Fc gamma receptors by

Arduin E, Arora S, Bamert PR, Kuiper T, Popp S, Geisse S, Grau R, Calzascia T, Zenke G, Kovarik J. Mol Immunol. 2015 Feb;63(2):456-63.

TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant. - TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant.

Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, Yoshikawa T, Hiroi T, Itoh N, Kawai Y, Mayumi T, Kamada H, Tsunoda S, Tsutsumi Y. Biochem Biophys Res Commun. 2009 Jul 3;384(3):296-300. doi: